Allylix has developed a proprietary technology platform that allows it to produce a group of high value, natural products called terpenes at low cost with sustainable supply. The company’s platform also enables the creation of novel compounds.

Allylix' technology has two key components:

1. The ability to engineer enzymes to produce a range of highly pure terpenes
2. The ability to produce those terpenes cost effectively using proprietary fermentation processes

Breakthrough biotechnology

The basis for Allylix’ technology began in the 1990’s at San Diego’s Salk Institute and the University of Kentucky where the company’s two scientific founders collaborated in terpene research over twelve years. They were among the first to provide a thorough understanding of the molecular structure of a class of enzymes, called terpene synthases, used by plants to produce terpenes.  They cloned a terpene synthase gene and determined the first three-dimensional structure of this class of enzyme.  As part of this research, they determined which elements of the enzymes were responsible for product specificity and developed technology to alter specificity, selectivity, and later catalytic efficiency of the enzymes.  The coupling of this protein engineering technology with yeast metabolic engineering for the production of terpenes provides the basis for a powerful platform for the production of a wide range of diverse terpene products. 

Expansive growth

Allylix launched its first product in 2009 and commercialized an additional product in 2010, with a pipeline of products to come in 2011 and 2012. In addition, the company will seek to license its technology to strategic partners outside its target industries.

The company’s technologies are protected by 37 issued U.S. and foreign patents that provide Allylix with a strong position and protection in key markets, including claims covering structure-based composition of matter, methods, proprietary enzymes and resulting products. Allylix’ intellectual property also includes trade secrets that cover host strains, expression systems and manufacturing processes.

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